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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC1
All Species:
16.97
Human Site:
T457
Identified Species:
37.33
UniProt:
P18887
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18887
NP_006288
633
69526
T457
K
P
P
T
P
E
E
T
K
A
A
S
P
V
L
Chimpanzee
Pan troglodytes
XP_512717
596
65689
T420
K
P
P
T
P
E
E
T
K
A
A
S
P
V
L
Rhesus Macaque
Macaca mulatta
XP_001100256
645
69984
H487
K
E
W
V
L
D
C
H
R
M
R
R
R
L
P
Dog
Lupus familis
XP_533653
654
71801
T478
R
P
K
T
P
E
E
T
K
P
A
S
P
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q60596
631
68952
T456
R
P
P
T
P
K
E
T
K
A
P
S
P
G
P
Rat
Rattus norvegicus
Q9ESZ0
631
68817
T456
R
P
P
T
P
E
E
T
K
A
P
S
P
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516926
549
59237
P397
P
E
E
T
Q
S
A
P
S
A
R
D
G
D
T
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080711
651
73244
S458
E
K
R
A
P
I
K
S
E
D
E
D
T
E
D
Zebra Danio
Brachydanio rerio
NP_001003988
615
68071
E447
K
Q
Q
P
V
E
E
E
E
E
E
E
E
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572217
614
68751
P438
V
I
S
G
I
Q
N
P
D
R
A
D
L
R
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001180271
512
56847
S359
D
V
D
E
Y
S
G
S
T
D
E
E
G
N
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.8
82.3
86
N.A.
86
86.5
N.A.
47.7
N.A.
53.9
51.1
N.A.
20.7
N.A.
N.A.
38.8
Protein Similarity:
100
94.1
83
88.3
N.A.
91.1
91
N.A.
56.5
N.A.
67.7
68.8
N.A.
36.9
N.A.
N.A.
55.1
P-Site Identity:
100
100
6.6
66.6
N.A.
66.6
73.3
N.A.
13.3
N.A.
6.6
20
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
26.6
73.3
N.A.
80
80
N.A.
13.3
N.A.
33.3
26.6
N.A.
13.3
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
10
0
0
46
37
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
0
10
0
0
10
19
0
28
0
10
19
% D
% Glu:
10
19
10
10
0
46
55
10
19
10
28
19
10
19
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
10
0
0
0
0
0
19
28
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
10
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
37
10
10
0
0
10
10
0
46
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
10
0
0
0
0
0
0
0
10
10
19
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% N
% Pro:
10
46
37
10
55
0
0
19
0
10
19
0
46
0
37
% P
% Gln:
0
10
10
0
10
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
28
0
10
0
0
0
0
0
10
10
19
10
10
10
0
% R
% Ser:
0
0
10
0
0
19
0
19
10
0
0
46
0
0
10
% S
% Thr:
0
0
0
55
0
0
0
46
10
0
0
0
10
0
10
% T
% Val:
10
10
0
10
10
0
0
0
0
0
0
0
0
19
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _